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CWR – Impacting US Veterans 2024

Funder(s): Cures Within Reach,

This Request for Proposals (RFP) from Cures Within Reach (CWR) is seeking clinical repurposing trials from US-based research institutions using already approved treatments to address unmet and high-priority medical needs of US veterans and/or active US military, such as mental health, post-traumatic stress disorder (PTSD) and brain injuries. Our strongest preference is for proof of concept, pivotal, Phase I or Phase IIA clinical repurposing trials. Clinical trials utilizing telehealth or other decentralized / remote
strategies are encouraged to apply.

Repurposed therapies must be approved and/or generally recognized as safe for human use by some
regulatory agency, such as the US Food and Drug Administration, European Medicines Agency, Health
Canada or Japan’s Pharmaceuticals and Medical Devices Agency, and may include drugs, devices,
nutraceuticals, diagnostics or cellular/gene therapies, as well as combination therapies. These repurposed therapies must be tested in a new indication for which they are not already approved or used widely in the clinic as standard of care.

CWR is accepting budgets of up to $75,000 for this funding opportunity, which includes the required
institutional match (see Important Funding Information below). Specific budget definitions for different
types of costs can be found in the Letter of Intent (LOI) submission instructions on ProposalCentral. For
Principal Investigators (PIs) who are interested in including underserved patients (as defined by the NIH) in the proposed clinical trial, CWR may provide an optional $5,000 – $15,000 in additional financial support for approved community engagement costs. Interested PIs may include any ideas and/or plans for engagement / collaborations with community-based organizations to engage underserved communities in the clinical
trial. However, community engagement is not required, and community engagement costs should not be
included in the requested funding amount submitted to CWR in the LOI. If a clinical trial is selected for
funding, CWR will contact the PI about potential community engagement.

CWR has a 2-stage submission process, starting with the LOI. Full scientific details are not required at the LOI stage. All submissions for this RFP are via our online grant management platform on ProposalCentral at using the Veterans Specific Repurposing Research program. Click on the “Apply Now” button on the right to begin a submission. For LOI submission instructions and more information about CWR’s funding opportunities generally, visit

LOIs for this RFP will be reviewed, scored and ranked by CWR staff, our external Grant Review Committee and/or our Science Advisory Board members, and the top-rated LOI submissions will be invited to submit a full proposal as the second stage. PIs will be contacted approximately 6-8 weeks following the LOI submission deadline with a decision.
The LOI submission deadline is 11:59pm U.S. Eastern Time on May 8, 2024. Contact Clare Thibodeaux, PhD at with any questions.

Timeline & Milestones

Call Open

April 7, 2024

Deadline First stage (LOI / pre-proposal)

May 8, 2024

Announcement of Applicants selected for stage 2

To be decided

Deadline Full Application

To be decided

Grant Decision – Final Decision – Awarding

To be decided

Interested in joining this call? Contact the funder(s) now