“Repurposing Research to Address Diversity, Equity and Inclusion (DEI) in the Chicago Area” is one of 4
tracks for Cures Within Reach’s 2024 funding opportunity for Chicago area institutions and PIs. Specific
focus areas for the other tracks include Early Stage Investigators, Pediatrics and Veterans issues. When
submitting a Letter of Intent, applicants should select “Chicago area” and “Other” for the “Type of Request
for Proposals” question, and then list all the applicable track(s) for their research in the “Other” text box:
DEI, Early Stage Investigator, Pediatrics and/or Veterans. Visit https://bit.ly/cwrrfps to learn more about
each track.

This Request for Proposals (RFP) from Cures Within Reach (CWR) is seeking clinical repurposing trials from
any research institution in the greater Chicago area to address Diversity, Equity and Inclusion (DEI),
including repurposing clinical trials that EITHER 1) are led by an underrepresented researcher OR 2)
address health disparities among underrepresented patients OR 3) both 1) and 2). While the funded
institutions must be in Chicagoland, patients and collaborators can be both within and outside the Chicago
area. Our strongest preference is for proof of concept, pivotal, Phase I or Phase IIA clinical repurposing trials.
Clinical trials utilizing telehealth or other remote strategies are encouraged to apply.

Repurposed therapies must be approved and/or generally recognized as safe for human use by some
regulatory agency, such as the US Food and Drug Administration, European Medicines Agency, Health
Canada or Japan’s Pharmaceuticals and Medical Devices Agency, and can include drugs, devices,
nutraceuticals, diagnostics or cellular/gene therapies, as well as combination therapies. These repurposed
therapies must be tested in a new indication for which they are not already approved or used widely in the
clinic as standard of care.

CWR is accepting budgets of up to $100,000 for this funding opportunity, which includes the required
institutional match.

All submissions for this RFP are via our online grant management platform on ProposalCentral at
https://bit.ly/submittocwr using the Geographic Specific Repurposing Research program. Click on the
“Apply Now” button on the right to begin a submission. PIs should select “Chicago area” and “Other” for the
“Type of Request for Proposals” question, and then list the applicable Chicago-focused track(s) for their
research in the “Other” text box: DEI, Early Stage Investigator, Pediatrics and/or Veterans. PIs can include as
many tracks as appropriate. For LOI submission instructions and more information about CWR’s funding
opportunities generally, visit https://bit.ly/cwrrfps.

CWR has a 2-stage submission process, starting with the LOI. Full scientific details are not required at the
LOI stage. LOIs for this RFP will be reviewed, scored and ranked by CWR staff, our external Grant Review
Committee and/or our Science Advisory Board (SAB) members, and the top-rated LOI submissions will be
invited to submit a full proposal as the second stage. PIs will be contacted approximately 6-8 weeks
following the LOI submission deadline with a decision.

The LOI submission deadline is 11:59pm U.S. Central Time on June 7, 2024. Contact Clare Thibodeaux, PhD
at clare@cureswithinreach.org with any questions.