NIHR NICE rolling call (EME Programme): The Efficacy and Mechanism Evaluation Programme is accepting Stage 1 applications to this funding opportunity. The programme is interested in receiving applications to meet recommendations in research identified in NICE guidance that has been published or updated since 2015.

Proposals must be within the remit of the EME Programme and the primary outcome measure must be health related. This call is also open in the Health Technology Assessment (HTA), Health and Social Care Delivery Research (HSDR) and Public Health Research (PHR) programmes for proposals which fall within the remit of those programmes – applicants should apply directly to the relevant programme. All proposals submitted must fall within the scope of the EME Programme.

The Efficacy and Mechanism Evaluation (EME) Programme funds ambitious studies evaluating interventions with potential to make a step-change in the promotion of health, treatment of disease and improvement of rehabilitation or long-term care. Within these studies, EME supports research in the mechanisms of diseases and treatments. EME is a partnership between the Medical Research Council (MRC) and the NIHR.The EME Programme looks to attract studies with novel methodological designs that deliver results more efficiently, reduce the study timeline, and maximise the knowledge gained. The translational research it supports covers a wide range of new and repurposed interventions, such as diagnostic or prognostic tests and decision-making tools, therapeutics or psychological treatments, medical devices, and public health initiatives delivered in the NHS.