This request for proposal (RFP) was designed based on patient needs. It will focus on interventions for the prevention and/or treatment of cancer-related chronic pain. Specifically, the RFP welcome proposals focused on all types of cancer-related chronic pain, including but not limited to post-surgical pain, lymphedema-related pain, chemotherapy-induced peripheral neuropathy, phantom pain, aromatase inhibitor-related joint pain, referred pain and bone metastasis pain.

We welcome applications for interventional clinical trials focusing on:
– Increasing the use of integrative medicine through evidence.
– Repurposing of off-patent compounds.

Study outcomes should include well-validated clinical and patient-reported outcomes. We encourage trials that include adult, geriatric, or pediatric populations. Phase II or III clinical trials are strongly encouraged. Other well-designed studies, such as comparative effectiveness trials, may be considered.