Platform studies to efficiently evaluate the efficacy of multiple interventions: The Efficacy and Mechanism Evaluation Programme is accepting Stage 1 applications to their commissioned workstream. All proposals submitted must fall within the scope of the EME Programme, and further information on this can be found by clicking on ‘What we fund’.

The Efficacy and Mechanism Evaluation (EME) Programme funds ambitious studies evaluating interventions with potential to make a step-change in the promotion of health, treatment of disease and improvement of rehabilitation or long-term care. Within these studies, EME supports research in the mechanisms of diseases and treatments. EME is a partnership between the Medical Research Council (MRC) and the NIHR.The EME Programme looks to attract studies with novel methodological designs that deliver results more efficiently, reduce the study timeline, and maximise the knowledge gained. The translational research it supports covers a wide range of new and repurposed interventions, such as diagnostic or prognostic tests and decision-making tools, therapeutics or psychological treatments, medical devices, and public health initiatives delivered in the NHS.