Berend Snijder is Assistant Professor at the ETH Zurich in Switzerland. The Snijder Lab is pioneering multiplexed image-based drug screening in patient biopsies, a technique we call pharmacoscopy, for both systems biology and personalized medicine. In two intervention trials, pharmacoscopy-guided treatments have shown promising improvements in the outcomes for patients suffering from blood cancers (Snijder et al., Lancet Haematology 2017; Kornauth et al, Cancer Discovery 2022; Schmid et al., Haematologica, 2023). We now combine these functional drug response profiles with multi-OMICs integration and deep learning-based image analyses, aiming to identify the molecular and cellular systems that underly drug-response individuality and improve patient treatment.
